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A member asked:

What is the difference between loratadine and benadryl (diphenhydramine)?

3 doctors weighed in across 2 answers

Different antihistam: Both are antihistamines. Benadryl (diphenhydramine) is a sedating shorter acting antihistamine and Loratadine is a longer acting non sedating antihistamine.

Dr Fowler agreed

Answered 9/4/2015

4.9k views

Thank
Dr. Stuart Kanter answered

Specializes in Internal Medicine - Geriatrics

Different drug class: Although both are antihistamines, they are different chemicals. Benadryl (diphenhydramine) is sedating. Loratadine is not.

Answered 9/30/2020

4.7k views

Thank

Related Questions

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Taking 120 mg pseudoephedrine every 12 hours, 10 mg loratadine in morning, and one Benadryl (diphenhydramine) at bedtime, is this ok?

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Can loratadine be used for a food allergy in place of benadryl (diphenhydramine)?

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I was prescribed Loratadine for irritant dermatitis on chest.are those pills safe-how often side effects appear from them?is Benadryl (diphenhydramine) better?

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I gave my one year old half of an ml of children's benadryl (diphenhydramine). I did not realize her dad gave her loratadine a few hours before. Will it hurt her?

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A member asked:

My doctor put me on loratadine 10mg antihistamine, one tablet every 24 Benadryl (diphenhydramine) after I've already taken loratadine for 2 days now. Is this safe?

A doctor has provided 1 answer

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