Yes, w/chronic use: With long-term use, morphine can cause liver toxicity. Liver enzymes may become elevated and there may be some anatomical damage too. http://www.ncbi.nlm.nih.gov/pubmed/15886461.
Answered 5/2/2020
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Morphine: No. Morphine has not been linked to liver damage.
Answered 5/19/2019
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