SOB: Exercise can't cause pleurisy which is due to rubbing of the inflamed (usually infected) outer lining surfaces of the lungs. But vigorous exercise can make intercostal muscles (muscles between your ribs) and costochondral joints (where ribs attach to your sternum (breastbone)) sore which mimics pleurisy as it may hurt to take a deep breath or cough.
Answered 8/11/2020
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