A member asked:

I take gabapentin 300 mg twice a day for severe bilateral peripheral neuropathy pain. is 900 mg a day safe for kidneys? i'm stage 3, pkd patient.

9 doctors weighed in across 2 answers

Yes : Recent studies suggest that 1800 mg is the most ideal dosage for most purposes naturally if a smaller dosage is working so much the better the drug is not nephrotoxic.

Answered 5/8/2016

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Increase Gabapentin?: Gabapentin (g) toxicity in patients with chronic kidney disease (ckd) is under recognized. Patients with CKD often receive inappropriately high g dosage for their kidney function, occasioning overt toxicity; advanced age and comorbidity predispose CKD patients to toxicity. I would ask your nephrologist's (c) opinion before increasing the dose, as the n knows you the best.

Answered 3/21/2018

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