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A member asked:
Are hives a common side effect of opioids due to histamine release?
3 doctors weighed in across 2 answers
No: Although opiates may worsen the hives, they more likely cause gastrointestinal symptoms and rarely if ever hives.
Answered 4/1/2016
4.9k views
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No: Opioids cause the mast cell to degranulate. The itch of opioids is a direct effect on releasing histamine from the mast cell. Hives are an allergic reaction from many causes.
Answered 9/7/2013
4.9k views
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People also searched for:
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