Can you take demerol (meperidine hydrochloride) and oxycodone together?

Both potent : Pain killers. Risk and side effects potentiate when used in combination. A pain physician should follow you closely and approve the combination. Good luck.

Demerol (meperidine hydrochloride) with oxy: These two drugs both act at the same receptor within the body. Taking them together can potentially be lethal. They should only be taken as prescribed by your physician.