Can you be diagnosed with lupus with positive ana, a lot of symptoms for lupus, but negative dsdna?

Lupus: A rheumatologist can answer this question after a complete exam and reviewing your symptoms and test, don't go by blood test results

Yes: Though the dsdna is helpful in assessing severity of lupus in some patients, it is not a requirement to have dsdna to be diagnosed with lupus. In fact, laboratory tests help confirm a suspected diagnosis of lupus but lab tests never make or disprove the diagnosis by themselves.