Does it itch?: If itching at night it could be a skin mite. Is anyone around you having the issue? Any new detergents. It's likely either a "contact dermatitis", or allergic reaction to something topical, a systemic allergic reaction (low chance) or a skin mite ( my guess) such as scabies. If itching like crazy, may need permetharin cream but i would go see doc.
Answered 6/14/2016
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Allergic reaction: Although possibly some other causes, a generalized rash could be caused by the drug benadryl (diphenhydramine).
Answered 9/5/2013
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