What is glutamate rebound?

Glutamate: Is a stimulating neurotransmitter that can be suppressed with considerable alcohol usage. The rebound occurs in the aftermath, and this and other factors account for the hangover. Symptoms include difficulty sleeping deeply enough to feel refreshed, jitteriness, etc.

Glutamate "rebound": As the name implies, glutamate receptors blocked during ingestion of alcohol (or ketamine) are reactivated ("rebound") after the effects of both are diminished, and high levels of glutamate are then felt with the perceptions of post alcohol withdrawal ("hangover") similar to when one eats foods containing high mono sodium glutamate, a preservative contained in many foods.