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A 34-year-old female asked:

How long does it generally take for warfarin to leave the body once you stop taking it?

2 doctor answers3 doctors weighed in
Dr. David Brouwer
Internal Medicine 31 years experience
Warfarin: The duration of time it takes for warfarin to be eliminated from your body depends on a few factors. It depends on the dose that you were previously taking, it depends on the pro time level at the time that you stop warfarin, and it depends on how much vitamin k is in your diet. That being said, usually we estimate 5 to 7 days for reduction of the effect of warfarin down to a level of baseline.
Dr. J Roberts
Vascular Surgery 28 years experience
72-96 hours : Warfarin antagonizes vitamin k dependent clotting factors in the liver. Factor ii or fibrinogen last the longest, 72 hrs. Once off drug, fibrinogen synthesis restarts after wash out of drug, which permits normalization of the pro time/inr...

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Last updated Dec 16, 2020

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