A member asked:

How can you tell mono from a cbc with differential?

A doctor has provided 1 answer
Dr. Brian Affleck answered

Specializes in ENT and Head and Neck Surgery

Atypical lymphocytes: The finding of a peripheral blood smear that is diagnostic of mononucleosis is atypical lymphocytes. They are atypical because when you smear them on the glass slide, they seem to flatten irregularly and look squashed.

Answered 10/27/2020

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