A member asked:

Should one use marijuana with alpha one lung disease?

5 doctors weighed in across 2 answers
Dr. Lokesh Guglani answered

Specializes in Pediatric Pulmonology

NO: Assuming that "alpha one lung disease" that you mentioned is alpha-one antitrypsin deficiency (a1at), then all forms of smoking should be avoided. This is because (depending on your phenotype) a1at disease will usually cause progressive lung damage & emphysema over time. Smoking can worsen your lung disease & hasten the progression of the emphysematous changes.

Answered 5/6/2016

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No: Smoke from any source can cause increased lung damage in patients with alpha-1 antitrypsin deficiency.

Answered 12/18/2014

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