Yes: A very rare cause of false negative results occurs when very, very, high concentrations of HCG are present. This is called the high-dose hook effect. Urine and blood can be negative. Diluting the urine and/or getting an ultrasound can confirm pregnancy. http://www.pregnancylab.net/2011/05/false-negative-pregnancy-tests.html.
Answered 10/3/2016
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