Either one: There should not be much difference between taking it in the am or the pm. Once Cymbalta (duloxetine) gets to a therapeutic point, keeping it in your system regularly is important and the same time each day is important, but day or night will not change much. If it causes you to be drowsy at all, then take it at night. If it causes you problems sleeping, then take it in am. I ope this helps and best of luck!
Answered 4/30/2020
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