A member asked:

What time of day should i take cymbalta (duloxetine) when taking hydrocondone all through out the day 3 a day and 2 klonopins in the evening time?

4 doctors weighed in across 3 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Cymbalta (duloxetine): Some sedation is expected at higher dosage. Best to take main dose in evening.

Answered 11/12/2012

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Dr. Miriam Borton answered

Specializes in Psychiatry

In AM: Each individual responds differently to each antidepressant. Cymbalta (duloxetine) should be taken in the am, however if it makes you tired you can take it in the pm (afternoon or night).

Answered 10/3/2016

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Dr. Vivek Prasad answered

Specializes in Psychiatry

Divided doses: Cymbalta (duloxetine) has fda approval for neuropathic pain and depression. It is usually dosed initially 40mg/d in 1-2 doses with the max dose generally 120mg/day per stahl's prescribers guide. Again the dosing depends on your side efts to the med regimen: nausea, diarrhea, decreased appetite, sedation, increased bp, sweating, sexual dysfunction.

Answered 6/24/2014

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