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A 26-year-old member asked:

What time of day should i take cymbalta (duloxetine) when taking hydrocondone all through out the day 3 a day and 2 klonopins in the evening time?

3 doctor answers4 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Cymbalta (duloxetine): Some sedation is expected at higher dosage. Best to take main dose in evening.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Miriam Borton
Psychiatry 47 years experience
In AM: Each individual responds differently to each antidepressant. Cymbalta (duloxetine) should be taken in the am, however if it makes you tired you can take it in the pm (afternoon or night).
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Vivek Prasad
Psychiatry 17 years experience
Divided doses: Cymbalta (duloxetine) has fda approval for neuropathic pain and depression. It is usually dosed initially 40mg/d in 1-2 doses with the max dose generally 120mg/day per stahl's prescribers guide. Again the dosing depends on your side efts to the med regimen: nausea, diarrhea, decreased appetite, sedation, increased bp, sweating, sexual dysfunction.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Oct 3, 2016

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