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A member asked:
Why does lyrica (pregabalin) sometimes give depression as side-effect. and for instance ghb is sometimes used as an anti-deppresant? is it that big of a diffrence?
8 doctors weighed in across 2 answers
Lyrica (pregabalin): Lyrica (pregabalin) enhances GABA in the brain which is supposed to calm the brain and may cause tiredness and depressive like symptoms as side effects ghb is used to treat insomnia i believe and not commonly prescribed.
Answered 2/18/2015
4.9k views
Most anticonvulsants: Cause depression in at least a small number of people. Ghb is a totally different medication and I have never heard of it being used as an antidepressant, at least in the us.
Answered 11/27/2017
4.9k views
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