I have a thyroid nodule that has increased in size from mm's to 1.6cm and hypoechoic associated with calcification. increased blood flow also?

Since it has: Enlarged, it needs to be biopsied. It's probably benign (at least statistically speaking) but you can't be too safe or too cautious. Talk w/your doctor and make sure your lab contains a serum thyroglobulin level (which can be a useful tumor marker).

Needle Biopsy: It is likely that there will be a recommendation for a needle biopsy of the nodule. This is done usually under ultrasound guidance and local anesthesia as an out-patient procedure. If there is evidence of a cancer then further treatment such as surgery will be required. Good luck.