A member asked:

Why avascular necrosis in sickle cell disease involve long bone only?

7 doctors weighed in across 2 answers
Dr. Michael Dugan answered

Specializes in Hematology

The ends of : The long bones have the most tenuous blood supply, and thus are at the greatest risk.

Answered 8/17/2013

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Dr. Craig MacArthur answered

Specializes in Pediatric Hematology and Oncology

Not only long bones: Sickle cell avn can occur in any bone that has limited blood supply. The obstruction to blood flow caused by sickle cells can cause the bone to die and distort normal shape and function, causing pain. The head of the femur (a long bone) and the talus bone (not long bone) in the ankle are common sites of avn in my sickle cell patients.

Answered 11/28/2017

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