Sickle cell disease bone marrow transplant. is that working out or not?

No clear results.: There is not level 1 evidence to show bone marrow transplant increases survival in patients with sickle cell disease. Although there are several reports with success a systematic randomized trial remains to be done. Bone marrow transplant is a procedure with multiple complications. After the procedure the recipient has to take meds for life. Cost/effective therapy analyses are not present.

Dr Fowler agreed

For select patients: Bone marrow transplant can cure patients with sickle cell disease, however this procedure has significant risks (including death). There is emerging evidence that the earlier one is transplanted for sickle cell disease, the better the outcome. This is a difficult decision to make since many with sickle cell have mild disease. Deciding who should be transplanted and when is not straight forward.