A member asked:

Does 40mg vs 20mg omeprazole reduce more stomach acid or last longer? does reducing too much stomach acid interfere with food digestion?

6 doctors weighed in across 3 answers

ACID REFLUX: 40 mgs of Omeprazole will reduce acid production more efficiently than 20 mgs.Acid reduction does not usually interfere with digestion of food.

Answered 9/28/2016

4.9k views

Thank

Omeprazole: A higher dose will be more effective in reducing stomach acid, and may, depending on your therapeutic threshold, last longer. However higher doses = higher chance of side effects which can include gas, diarrhea or constipation. Too high a dose and you lose the protective effects of stomach acid against bacteria, leading to a higher risk of c. Difficile and ppi pneumonia with long time use.

Answered 9/9/2019

4.9k views

Thank

No: The most important aspect is reducing gerd symptoms to reduce the chronic esophagitis causing the barrett's changes that increase risk of esophageal cancer. Some patients need 20 mg others need 40 mg omeprazole. Every patient is different. It won't interfere with digestion.

Answered 2/22/2019

4.9k views

Thank

Related Questions