See below: The incompatibility occurs when the mother is exposed to the blood of the new baby. This usually occurs at delivery. The mother then makes antibodies to that "foreign substance" and this can adversely affect the next pregnancy as the mother's immune system will see it as a "foreign" body and want to get rid of it. This problem is usually treatable with an injection at the birth of the first child.
Answered 4/24/2015
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