U.S. doctors online nowAsk doctors free
Mount Vernon, IL
A 23-year-old female asked:

What does it mean if my complement c3 serum was 4 points low on a scale of 90-180 and my c4 was normal? could there be something wrong?

2 doctor answers • 2 doctors weighed in
Dr. Nayla Mumneh
Dr. Nayla Mumnehanswered
Allergy and Immunology 31 years experience
Not really: If all other tests are negative and there is no evidence of autoimmune antibodies, one number does not carry enough meaning to be worrisome.
Created for people with ongoing healthcare needs but benefits everyone.
Learn how we can help
5.4k viewsAnswered >2 years ago
Thank
Dr. Neal Birnbaum
Dr. Neal Birnbaumanswered
Rheumatology 53 years experience
Probably nothing: Decreased complement levels are seen in patients with active lupus. However, very minor abnormalities occur frequently, even in perfectly healthy individuals. These lab values must be viewed in the context of other lab studies and the clinical picture. Ask the physician who ordered the complement studies for his/her opinion as to the clinical relevance of this isolated lab abnormality.
Created for people with ongoing healthcare needs but benefits everyone.
Learn how we can help
5.4k viewsAnswered >2 years ago
Thank

Related questions

A 43-year-old male asked:
What is the significance of having low serum levels of kappa and lambda free light chains? I had high ch50 and normal C3 and c4.
1 doctor answer • 1 doctor weighed in
A 41-year-old female asked:
WBC has been hi whole life. Latest result: Hi WBC, low RDW, hi Neutrophils, 2+ Occult Blood, positive ANA direct, hi Complement C3, Serum, hi antichromatin antibody. C reactive protein & sed rate normal. Does this point to anything or inconclusive?
1 doctor answer • 1 doctor weighed in
A 30-year-old female asked:
My C4 complement level is low and C3 complement is at the low end of the range (90, ref range 90-180). What could this mean?
2 doctor answers • 4 doctors weighed in
A 35-year-old male asked:
What means very high CH50 complement? Mine is 277 CAE,C3 and C4 normal.Ref ranges for lab are only greater than 60,but I read high could be pathologis
1 doctor answer • 1 doctor weighed in
A 21-year-old male asked:
Complement C3 & C4 tests done 3 times. C3 normal but twice C4 was borderline normal or borderline low, 3rd time it was well within range. deficiency?
1 doctor answer • 1 doctor weighed in
Last updated Jan 21, 2013

Found in:

Serum

People also asked

I have normal levels of complement C2 and c4. C3 level is low. Ch50 is high-normal(57 u/ml)-(all are serum tests)-what are the possible causes?
1 doctor answer • 1 doctor weighed in
Do serum complement levels naturally fluctuate? had one mildly low C4 with normal C3 but when test redone both had risen & C4 was within normal range
1 doctor answer • 1 doctor weighed in
Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?
1 doctor answer • 2 doctors weighed in
What illness could explain ELEVATED C3 and C4 complement serum levels in the presence of angioedema? ANA and Rheum Arth Factor both negative.
1 doctor answer • 1 doctor weighed in
Is it normal to have low C3&C4 serum? I had a positive ANA over five years ago also. Now just have low C3&4. Should I be worried? I have felt sick. TY
1 doctor answer • 1 doctor weighed in
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
Talk to a doctor now
24/7 visits - just $44!
50% off with $19/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.

Get the Free App for Members

Get the Free App for Doctors

HIPAASecure
SOC 2 Type 2Certified
TermsPrivacyCookiesDMCA
Copyright 2023 HealthTap, Inc.