A 38-year-old member asked:
The increased risk of having a child with genetic defects like down syn. also applies to men over age 40?
1 doctor answer • 2 doctors weighed in
Pediatric Cardiology 17 years experience
Yes: The simple answer is yes, but for different and incompletely understood reasons. "advanced paternal age" has been associated with genetic defects in general, though not specifically Down syndrome as in women. The reasons remain to be determined, but as with anything else, scientific literature suggests that sperm "quality" degrades over time with increased risk of various defects.
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4.9k viewsReviewed >2 years ago
Last updated Feb 18, 2015
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