A member asked:

The increased risk of having a child with genetic defects like down syn. also applies to men over age 40?

A doctor has provided 1 answer
Dr. Sarosh Batlivala answered

Specializes in Pediatric Cardiology

Yes: The simple answer is yes, but for different and incompletely understood reasons. "advanced paternal age" has been associated with genetic defects in general, though not specifically Down syndrome as in women. The reasons remain to be determined, but as with anything else, scientific literature suggests that sperm "quality" degrades over time with increased risk of various defects.

Answered 2/18/2015

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