A member asked:

I take 100mg of trazodone but doesn't work as well now. can i safely up the dose to 150 or 200?

6 doctors weighed in across 3 answers
Dr. Adrian Preda answered

Specializes in Psychiatry

It all depends: I mention a diagnosis of bipolar. If you take it for depression the dose should be in the range of 200-400 as long as you are also taking a mood stabilizer. Would not be my first choice if you are trying to use it as a sedative (in light of your bipolar history).

Answered 1/25/2021

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Dr. Pamela Pappas answered

Specializes in Psychiatry

Bipolar D/O: Your additional patient information does say you are bipolar, but there are no mood stabilizers on your medication list. I would be cautious about raising your trazodone dose. Sleep disturbance can signify a hypomanic or manic episode developing, and you would not want to precipitate that. I encourage you to work with a psychiatrist on this, and find better treatments than trazodone alone.

Answered 8/9/2013

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Dr. Alan Ali answered

Specializes in Psychiatry

Trazodone: Highest dose is300mg. Talk to your doctor first.

Answered 5/12/2015

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