Can major depression cause memorie loss?

Yes: Major depression can precipitate a cognitive dysfunction that can be quite severe. In fact, in more severe cases of depression the term pseudodementia has been coined to describe this phenomenon. You would benefit from evaluation by a physician if you struggle with memory loss to evaluate all possible causes and implement appropriate treatment as indicated. I wish you the best!

Yes: Depression causes the loss of brain cells in the limbus system which includes the hippocampi. Treatment, whether medicinal or psychotherapy, triggers the brain to release brain- derived neurotrophic factor, essentially nerve growth factor in the brain which helps return memory to where it was before you got sick. It helps brain cells grow back!