A member asked:

My neighbors say my new doctor tends to overdiagnose everyone. he thinks i might have biliary cirrhosis. can you tell me the symptoms?

7 doctors weighed in across 2 answers

Early sxs of PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching +/- jaundice, RUQ pain.

Answered 6/23/2020

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Dr. Arthur Heller answered

Specializes in Gastroenterology

Fatigue, itch, yello: Agree dr. Cattano. Autoimmune disease. Symptoms may be mild, nonspecific, include fatigue, itching, jaundice (yellow eyes and skin), joint aches, weight loss, depress, anemia, skin abn, of chol . Can be assoc with high cholesterol, low vitamin d, osteoporosis, other autoimmune diseases. Confirmed with blood tests, usually liver biopsy. Wait for blood test results (ama, ana, asma, and others.

Answered 7/29/2016

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