Early sxs of PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching +/- jaundice, RUQ pain.
Answered 6/23/2020
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Fatigue, itch, yello: Agree dr. Cattano. Autoimmune disease. Symptoms may be mild, nonspecific, include fatigue, itching, jaundice (yellow eyes and skin), joint aches, weight loss, depress, anemia, skin abn, of chol . Can be assoc with high cholesterol, low vitamin d, osteoporosis, other autoimmune diseases. Confirmed with blood tests, usually liver biopsy. Wait for blood test results (ama, ana, asma, and others.
Answered 7/29/2016
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