Celexa (citalopram) & alcohol after effects: is it normal to have slightly depressed mindstate?

Yes: The combination can cause you to feel a little depressed for a few reasons. Celexa (citalopram) and alcohol both are metabolized in the liver. This will impair celexa's ability to work well as an antidepressant. Alcohol can magnify the side effects of medication, i.e. Making you feel more tired or down. Alcohol is also a depressant just by itself.