A member asked:

What symptoms does someone with canavan disease have?

4 doctors weighed in across 2 answers

Progressive delays.: Canavan disease, a genetic disorder caused by an enzyme deficiency in one kind of brain cell, is characterized by worsening developmental delays, worsening muscle tone, large head, and mental retardation. It is a devastating disease with degeneration of nerve tissue.

Answered 9/28/2016

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Multiple: Mental retardation.Loss of previously acquired motor skills feeding difficulties.Abnormal muscle tone(floppiness or stiffness)abnormally large, poorly controlled head.Paralysis.Blindness.Hearing loss.Progressive brain atrophy.No cure.Only symptomatic and supportive treatments.

Answered 7/20/2012

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