A member asked:

Clostridium difficile toxin b gene present clostridium dificile antigen presen. would u no how severe the c diff is?

A doctor has provided 1 answer

Have diarrhea or no?: C.Difficile is pathogenic in older children & adults (whose colonic microflora are altered by antibiotics, chemotherapy, salmonella/shigella). C.Diff causes diarrhea w/pseudomembranous & other colitis, complicates inflammatory bowel disease, causes fulminant transmural extension, perforation with peritonitis, toxic megacolon. Treatment, & confirmation of post-treatment eradication, is recommended.

Answered 1/6/2019

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