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A 21-year-old member asked:

Is it true that the use of fecal enemas is way to treat severe clostridium difficile infections?

3 doctor answers8 doctors weighed in
Dr. Timothy Ashley
Internal Medicine and Pediatrics 16 years experience
Absolutely True: It's amazing, and for some people seems disgusting, but it actually works to recolonize the gut. The formal name is fecal or stool transplant, and as you say it essentially involves introducing fecal matter from a healthy donor into the gut of a person with c. Diff. Still experimental and not widely used yet. I have condensed a medlineplus link: see http://tinyurl.Com/7r27abk.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. John Leander Po
Infectious Disease 19 years experience
It DOES work!: As an infectious diseases specialist, I have performed this procedure successfully. There is a scientific basis:normal bacteria in feces suppresses c diff. However, abx kill the normal flora and can lead to overgrowth of c diff. Fecal enemas uses stool from the pt's donor in-residence , restoring the "normal" flora in the pt. The risk is obvious: unscreened donor stool may have other germs.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Nelson Nicolasora
Infectious Disease 26 years experience
Yes.: Most studies albeit not large scale has shown that Fecal microbiota transplantation (FMT) has a success rate of >90% in preventing C diff relapses. These studies are mostly in relapsing mild to moderate cases. More recently, a study by Arionadis et. al "... FMT for SEVERE of complicated Clostridium difficile infection" DDW 2013; Abstract 998 showed a cure rate of 84% and looks promising.
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Mar 14, 2016
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