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A member asked:
Will the serum protein electrophoresis test tell me anything that the immunofixation test would not tell me?
6 doctors weighed in across 2 answers
Yes.: The ife is very sensitive at finding an abnormal antibody (monoclonal antibody) in blood, but it does not measure the quantity. The spep is less sensitive at finding the monocloprotein protein, but it is a quantitative test, so it answers "how much" monoclonal protein is present. The spep is used to monitor therapy for that reason.
Answered 2/11/2014
5k views
See below: Immunofixation is a more sophisticated test then serum protein electrophoresis re immunoglobulins.
Answered 1/29/2020
5k views
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What is the difference in the utility of these 2 tests: IgG subclass (1-4) serum blood test.......And......Serum protein electrophoresis?
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People also searched for:
What would be the diagnosis for slightly above nomal range serum Img M, normal Img A & G. SPE Electrophoresis pattern revealing possible abnormality. Protein test: Normal levels. Serum immunofixation: No paraprotein, no bands. normal pattern? Thanks
Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.
When do you use immunofixation protein electrophoresis instead of regular serum protein electrophoresis ? Is it more informative ? What about serum immunoglobulins?
Slightly elevated beta fraction from serum protein electrophoresis. Beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen. Immunofixation normal.
High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio.No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer?Normal WBC
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