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A member asked:
When do you use immunofixation protein electrophoresis instead of regular serum protein electrophoresis ? is it more informative ? what about serum immunoglobulins?
2 doctors weighed in across 2 answers
Certain low levels of globulins can be missed by electrophoreses hence the immunofixation method is used to detect them.
Answered 12/8/2022
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Immunofixation electrophoresis is more sensitive and specific for detecting monoclonal immunoglobulins. Not all monoclonal immunoglobulins are dangerous and the results need to interpreted in the clinical context.
Answered 12/10/2022
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