Is it okay to take acetaminophen pills that also have caffeine if you have stage 3/4 kidney disease? i believe tylenol itself is considered safe.

Tylenol (acetaminophen) is safe for: Patients with kidney disease. But nsaids- like ibuprofen/motrin, aleve (naproxen) are not safe for renal patients .They cause constriction of renal arteries, thus decreasing blood flow by antagonizing the effect of prostaglandin. Caffeine is ok for patients with kidney disease but too much of it can raise the blood pressure. Hope all is well with your family! take care!

Pain pills: Acetaminophen with caffeine is fairly safe - be sure there is no aspirin or NSAID or phenacetin in the pills; do not exceed 2100 mg Acetaminophen per day;