What causes agenesis of the corpus callosum?

Congenital: abnormality. Born with it. Callosal malformations are among the most common congenital brain anomalies and are associated with a wide range of neuropsychological deficits

Unknown cause: Etiology remains largely unknown. It seems to be related to inherited conditions, metabolic disorders, or exposure to toxins or viruses in the first trimester that affect normal fetal development.

Birth defect: Agenesis of the corpus callosum (ACC) is a rare birth defect (congenital disorder) in which there is a complete or partial absence of the corpus callosum.. This likely occurs in the first trimester but the exact cause cannot be known. ACC can cause problems with facial recognition, processing of complex information, vision impairment, poor muscle tone etc. There is no specific treatment.

It is a: developmental congenital abnormality, occurring in isolation or in association with various cerebral abnormalities/syndromes.Agenesis of the corpus callosum is caused by disruption to development of the fetal brain between the 3rd and 12th weeks of pregnancy. In most cases, it is not possible to know what caused an individual to have ACC.