A member asked:

How dangerous can stage 4 breast cancer that has mets to lungs and adrenal gland be if it goes untreated without chemo?

12 doctors weighed in across 3 answers

Hard to Predict: Among all patients with breast cancer who present with distant disease, one fourth will survive beyond 5 years. It would be good to know the patient's age and receptor status (er, pr, her2) to answer this question, because we are finding much better results now with certain treatments (like Herceptin (trastuzumab) for her2+ pts) than in the past. Ask your oncologist for info.

Answered 3/29/2018

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Dr. Andrew Hoffman answered

Specializes in General Surgery

Fatal?: Cancer that is so aggressive and wide spread is not likely to regress or give up on it's own. Without any chemo it may spread rapidly through the lung and to more organs. Even with chemo rx there may not be much help with such an advanced cancer.

Answered 10/4/2016

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Wide spread: Cancer is likely to lead to death regardless of treatment. Ask about benefit of chemo vs. Toxicity, and appropriateness of hospice.

Answered 12/10/2013

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