Yes, sometimes: There are two separate types of chronic leukemia;these go by the names CML and cll. They follow a separate course and can have a long course of disease. CML often ends up as acute leukemia(called blastic change which is a type of acute leukemia bearing poor survival once this transformation has taken place. Fortunately the risk of this happening is much reduced with the modern treatments for cml.
Answered 6/10/2014
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