A member asked:

I can no longer sleep and its causing mental problems? could this be due to taking diphenhydramine?

2 doctors weighed in across 2 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Insomnia: Regular use of Benadryl (diphenhydramine) along with melatonin is possible cause of tolerance. Sleep hygiene works well. Refer to diagram. Check with your doctor about other alternative medications.

Answered 4/16/2021

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The soporific effect eventually encounters tolerance, and higher doses result in less efficacy. Lack of sleep can result in both emotional and cognitive problems. At this point, find help with a sleep hygiene approach, and try to avoid sleeping pills. A sleep specialist may be available to provide the needed guidance.

Answered 4/16/2021

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