A member asked:

Is it normal or unusual for me to have to sleep most of the next day after my methotrexate 15 mg injection? day after that, the fatigue resolves.

A doctor has provided 1 answer

See below: You are describing the classic side effect of fatigue and how it occurs after taking methotrexate. Talk to your doctor if this continues to be bothersome.

Answered 6/26/2013

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