If you had sepsis in the leg before can it come back again? what are the risk afterwards especially if you have an chronic iinflammatory disease?

It can,,,: Sepsis defines a condition where bacteria has invaded the bloodstream or circulatory system. This can be treated and cured if found fast enough but it can easily happen again if another infection develops and isn't treated. If there is a chronic inflammatory disease, the body's ability to stop sepsis and fight new infections is reduced and there is greater chance for sepsis. Hope this helps.