A member asked:

If both hepatic portal vein and hepatic arteries have thrombosis how long would it take for the liver to become necrotic ?

4 doctors weighed in across 2 answers

Budd-Chiari: The surprising this is that it doesn't - the hepatic arteries don't matter as most of the blood comes via the portal vein, and the thrombi that plug the veins are either not totally occlusive or some collateral flow develops. So these folks are very sick, but the liver cells seldom actually die off.

Answered 6/20/2013

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Liver ischemia: There are 2 blood supplies to the liver. The portal vein which supplies about 80% and the hepatic artery which supplies about 20%. If both are occluded the liver can become ischemic and die. This can happen right away. If one is occluded in one of the larger branches though blood can find other routs to get to the liver tissue. Also, the thrombus may recannalize and some blood may get through.

Answered 9/3/2013

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