Aspirin allergy?: More severe reactions to Aspirin can occur but i agree it would be unlikely wtih your history. Recent evidence suggests that antihistamines and montelukast (singulair) pretreatment may prevent these hive-like reactions to Aspirin and other nsaids such as Ibuprofen or naproxen. If the Aspirin is for pain relief consider using Acetaminophen instead.
Answered 6/25/2014
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