A member asked:

Is 5 htp an alternative for ssri antidepressants?

4 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

5HTP vs SSRI's: People are intrigued with 5-htp because it can be decarboxylated to serotonin, a neurotransmitter with many important functions. There are some studies suggesting it can help with depression, especially combined with l-tyrosine. 5htp can certainly cause GI distress like ssri's can. However, there isn't enough evidence to say it equals ssri antidepressants in treating depression. 200-300mg/day.

Answered 3/19/2018

5.1k views

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Dr. Alan Ali answered

Specializes in Psychiatry

5HTP: As another option for mild depression, yes. As an alternative to SSRI, I doubt it would be as efficacious. One thing for sure, do not combine the two.

Answered 6/17/2015

2.8k views

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