What does a estradiol of 58 and a fsh serum of 28.2 mean?

Early menopause: Female hormone levels depend on where you are in your menstrual cycle. Are you having regular periods? The high fsh level could indicate being mid cycle if you are having periods, otherwise it can be a sign that your ovaries are failing (menopause). The Estradiol level is low for mid cycle, but could be appropriate for the early part of your menstrual cycle.