A member asked:

If negative for brca gene, yet father had prostate cancer, is his daughter still at risk for breast cancer? i heard they were linked.

2 doctors weighed in across 2 answers

BRCA gene links: A family history of breast ovarian or colon cancer can predispose future genetic progeny if the BRCA is positive. I am unaware of a negative BRCA link to prostate cancer in males producing breast cancer in the female progeny.

Answered 7/27/2014

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Not elevated risk: In families who DO have a BRCA mutation, the breast and prostate cancers can be linked. However both are very common cancers, so they can be seen within families even if BRCA negative. The average lifetime risk of breast cancer for any given woman is 12.5%. You can do a search for the Gail Risk Model to get a little better idea of your own personal risk.

Answered 8/1/2014

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