A member asked:

Have schizophrenia 21yrs. clozoril works, but low wbc. others bad side effects. any suggestions what to do? taken them all.nothing else works.

8 doctors weighed in across 2 answers
Dr. Mara Fiorentino answered

Specializes in Psychiatry

Clozapine: Clozapine is one of the the best antipsychotics in the market, even when it causes serious and bothersome side effects. If nothing else works, stay on it, and do not stop the medicine unless your doctor recommends it due to low wbc. If it is combined with lithium, it could increase the wnc count to normal levels to continue treatment. Be aware of the weight gain due to clozapine.

Answered 5/9/2016

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Dr. Pamela Pappas answered

Specializes in Psychiatry

How low?: It depends on how low of a WBC count you mean. Prescribing guidelines don't allow Clozaril (clozapine) to be dispensed if WBC count is <3500, or absolute neutrophil count is <2000. As long as your counts equal or surpass these limits, you are safe to continue, esp if it's working for you! please talk with your psychiatrist. For other issues: http://www.Nami.Org/template.Cfm?Section=hearts_and_minds.

Answered 11/28/2017

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