A member asked:

Can mammaprint be used on a core biopsy to help decide on mastectomy vs. pre-operative chemo/lumpectomy?

A doctor has provided 1 answer
Dr. Carlos Encarnacion answered

Specializes in Medical Oncology

Excellent question!!: I only know of 2 small studies (netherlands and us) in which mammaprint was evaluated in a pre-op setting. A "high risk" category was predictive of a pathologic complete response (desirable). I believe there is at least one ongoing trial (mint i) and maybe more studying that question. For now, microarray tests are used in the post-op setting for er+, node negative patients in routine practice.

Answered 12/10/2013

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