A member asked:

Gleason score eqivalent without biopsy?

7 doctors weighed in across 2 answers
Dr. George Klauber answered

Specializes in Pediatric Urology

Question unclear: Gleason score for prostate cancer depends upon a biopsy or tissue diagnosis of a surgical prostatectomy specimen. Gleason graded according to microscopic appearance of cancer grades between 1-5. 1 being least malignant. Score is obtained by adding grade # of most prevalent cell type to grade # of second most prevalent cell type. Thus grade4 + grade 3 gets a gleason score of 7.

Answered 9/30/2020

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Not possible: There is no way to get a gleason score without a biopsy. The grade is determined by the pathologist's interpretation of an actual tissue sample, and the two most commonly seen patterns are added together to get a gleason score.

Answered 5/10/2019

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