A member asked:

Taking entacort to treat crohn's disease. does this steroid enter bloodstream or only 'topical' within the intestine?

4 doctors weighed in across 2 answers
Dr. Jason Hemming answered

Specializes in Gastroenterology

Both: It acts locally but then it is completely absorbed by the intestine. Following this 80-90% is metabolized by the liver before it reaches the rest of the body (1st pass). However some systemic effect still occurs.

Answered 11/26/2013

6.1k views

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Dr. Ihor Zakaluzny answered

Specializes in General Surgery

Minimal absorption: Very little is absorbed, so that systemic side effects are unlikely.

Answered 10/3/2016

6.1k views

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