A 64-year-old member asked:
Can long term use of hyzaar (losartan and hydrocholorthiazide) cause permanent swelling in legs?
1 doctor answer • 2 doctors weighed in

Dr. Martin Ostroanswered
Allergy and Immunology 51 years experience
Not from Hyzaar (losartan and hydrocholorthiazide): Hyzaar (losartan and hydrocholorthiazide) is a combination of a diuretic/water pill and an angiotensin receptor blocker/arb which is used to lower blood pressure. The constant leg swelling may mean you are retaining fluid and need a higher dose of diuretic. The arb component has a 1-3% chance of causing angioedema, episodes of swelling involving various parts of the body (unusual to only affect legs) for 24-72 hr not constantly.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Last updated Feb 7, 2015
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $44!
50% off with $19/month membership
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.