Is there a genetic predisposition to a certain type of plaque-small or large fluffy type? a cousin is having tests done in texas.can types be altered?

Yes: Predisposition to certain type of plaue is certainly, but the other factors such as life style also play important roles in the development of plue.

Low Density Choleste: I think you're referring to LDL or low density cholesterol. It comes in many forms: the small dense form is associated with atherosclerosis (hardening of the arteries) more than the large fluffy kind. It can be altered through lifestyle and medicine. Do you have a strong family history and/or premature heart disease in the family? You should discuss your concern with your family doctor.